Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome

Protein homeostasis (proteostasis) is essential for the cell and is maintained by a highly conserved protein quality control (PQC) system, which triages newly synthesized, mislocalized and misfolded proteins. The ubiquitin-proteasome system (UPS), molecular chaperones, and co-chaperones are vital PQ...

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Publicat a:Biomolecules
Autors principals: Abildgaard, Amanda B., Gersing, Sarah K., Larsen-Ledet, Sven, Nielsen, Sofie V., Stein, Amelie, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463752/
https://ncbi.nlm.nih.gov/pubmed/32759676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10081141
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