Automated GMP-Compliant Production of [(68)Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans

Introduction: [(68)Ga]Ga-DO3A-VS-Cys(40)-Tuna-2 (previously published as [(68)Ga]Ga-DO3A-VS-Cys(40)-S01-GCG) has shown high-affinity specific binding to the glucagon receptor (GCGR) in vitro and in vivo in rats and non-human primates in our previous studies, confirming the suitability of the tracer...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmaceuticals (Basel)
Egile Nagusiak: Wagner, Michael, Doverfjord, Johan G., Tillner, Joachim, Antoni, Gunnar, Haack, Torsten, Bossart, Martin, Laitinen, Iina, Johansson, Lars, Pierrou, Stefan, Eriksson, Olof, Velikyan, Irina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463542/
https://ncbi.nlm.nih.gov/pubmed/32752075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13080176
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