Ensemble Learning Prediction of Drug-Target Interactions Using GIST Descriptor Extracted from PSSM-Based Evolutionary Information

Identifying the drug-target interactions (DTIs) plays an essential role in new drug development. However, there still has the limited knowledge of DTIs and a significant number of unknown DTI pairs. Moreover, the traditional experimental methods have inevitable disadvantages such as high cost and ti...

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Vydáno v:Biomed Res Int
Hlavní autoři: Zhan, Xinke, You, Zhuhong, Yu, Changqing, Li, Liping, Pan, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463380/
https://ncbi.nlm.nih.gov/pubmed/32908888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4516250
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