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Ensemble Learning Prediction of Drug-Target Interactions Using GIST Descriptor Extracted from PSSM-Based Evolutionary Information

Identifying the drug-target interactions (DTIs) plays an essential role in new drug development. However, there still has the limited knowledge of DTIs and a significant number of unknown DTI pairs. Moreover, the traditional experimental methods have inevitable disadvantages such as high cost and ti...

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Библиографические подробности
Опубликовано в: :Biomed Res Int
Главные авторы: Zhan, Xinke, You, Zhuhong, Yu, Changqing, Li, Liping, Pan, Jie
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463380/
https://ncbi.nlm.nih.gov/pubmed/32908888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4516250
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