Chargement en cours...

FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization

Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective c...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Pozniak, Marta, Sokolowska‐Wedzina, Aleksandra, Jastrzebski, Kamil, Szymczyk, Jakub, Porebska, Natalia, Krzyscik, Mateusz Adam, Zakrzewska, Malgorzata, Miaczynska, Marta, Otlewski, Jacek, Opalinski, Lukasz
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463352/
https://ncbi.nlm.nih.gov/pubmed/32511887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12740
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!