Genome‐wide profiling of circulating tumor DNA depicts landscape of copy number alterations in pancreatic cancer with liver metastasis

Cell‐free DNA (cfDNA) offers an alternative to tissue biopsies for genomic profiling in tumors. Here, we sought to evaluate copy number alterations in PDAC through whole‐genome sequencing (WGS) of cfDNA and determine their clinical significance. Using shallow WGS across 90 plasma samples from 70 pan...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Wei, Tao, Zhang, Jian, Li, Jin, Chen, Qi, Zhi, Xiao, Tao, Wei, Ma, Jingjiao, Yang, Jiaqi, Lou, Yu, Ma, Tao, Li, Xiang, Zhang, Qi, Chen, Wei, Que, Risheng, Gao, Shunliang, Bai, Xueli, Liang, Tingbo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463305/
https://ncbi.nlm.nih.gov/pubmed/32593194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12757
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