Genome‐wide profiling of circulating tumor DNA depicts landscape of copy number alterations in pancreatic cancer with liver metastasis

Cell‐free DNA (cfDNA) offers an alternative to tissue biopsies for genomic profiling in tumors. Here, we sought to evaluate copy number alterations in PDAC through whole‐genome sequencing (WGS) of cfDNA and determine their clinical significance. Using shallow WGS across 90 plasma samples from 70 pan...

詳細記述

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書誌詳細
出版年:Mol Oncol
主要な著者: Wei, Tao, Zhang, Jian, Li, Jin, Chen, Qi, Zhi, Xiao, Tao, Wei, Ma, Jingjiao, Yang, Jiaqi, Lou, Yu, Ma, Tao, Li, Xiang, Zhang, Qi, Chen, Wei, Que, Risheng, Gao, Shunliang, Bai, Xueli, Liang, Tingbo
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463305/
https://ncbi.nlm.nih.gov/pubmed/32593194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12757
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