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Promoter Proximal Pausing Limits Tumorous Growth Induced by the Yki Transcription Factor in Drosophila
Promoter proximal pausing (PPP) of RNA polymerase II has emerged as a crucial rate-limiting step in the regulation of gene expression. Regulation of PPP is brought about by complexes 7SK snRNP, P-TEFb (Cdk9/cycT), and the negative elongation factor (NELF), which are highly conserved from Drosophila...
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| Yayımlandı: | Genetics |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Genetics Society of America
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7463282/ https://ncbi.nlm.nih.gov/pubmed/32737120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303419 |
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