Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer

Despite decades of study, the molecular mechanisms and selectivity of the biomolecular components of honeybee (Apis mellifera) venom as anticancer agents remain largely unknown. Here, we demonstrate that honeybee venom and its major component melittin potently induce cell death, particularly in the...

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Pubblicato in:NPJ Precis Oncol
Autori principali: Duffy, Ciara, Sorolla, Anabel, Wang, Edina, Golden, Emily, Woodward, Eleanor, Davern, Kathleen, Ho, Diwei, Johnstone, Elizabeth, Pfleger, Kevin, Redfern, Andrew, Iyer, K. Swaminathan, Baer, Boris, Blancafort, Pilar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463160/
https://ncbi.nlm.nih.gov/pubmed/32923684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-020-00129-0
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