Improvement of Ocular Efficacy of Levofloxacin by Bioadhesive Chitosan Coated PLGA Nanoparticles: Box-behnken Design, In-vitro Characterization, Antibacterial Evaluation and Scintigraphy Study

Conjunctivitis is considered as a common infection of ocular surfaces. Eye drop is most commonly used for treatment of conjunctivitis, but has some drawback like 95% drug eliminated after administration. Administration of levofloxacin to the anterior site in form of chitosan coated poly (lactic-co-g...

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Vydáno v:Iran J Pharm Res
Hlavní autoři: Ameeduzzafar, Khan, Nazia, Alruwaili, Nabil K, Bukhari, Syed Nasir Abbas, Alsuwayt, Bader, Afzal, Muhammad, Akhter, Sana, Yasir, Mohd, Elmowafy, Mohammed, Shalaby, Khaled, Ali, Asgar
Médium: Artigo
Jazyk:Inglês
Vydáno: Shaheed Beheshti University of Medical Sciences 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462482/
https://ncbi.nlm.nih.gov/pubmed/32922488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.15318.13016
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