Stimulus Responsive Ocular Gentamycin-Ferrying Chitosan Nanoparticles Hydrogel: Formulation Optimization, Ocular Safety and Antibacterial Assessment

PURPOSE: The present study was designed to study the gentamycin (GTM)-loaded stimulus-responsive chitosan nanoparticles to treat bacterial conjunctivitis. METHODS: GTM-loaded chitosan nanoparticles (GTM-CHNPs) were prepared by ionotropic gelation method and further optimized by 3-factor and 3-level...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Alruwaili, Nabil K, Zafar, Ameeduzzafar, Imam, Syed Sarim, Alharbi, Khalid Saad, Alotaibi, Nasser Hadal, Alshehri, Sultan, Alhakamy, Nabil A, Alzarea, Abdulaziz I, Afzal, Muhammad, Elmowafy, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335305/
https://ncbi.nlm.nih.gov/pubmed/32636627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S254763
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