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α-Branched amines by catalytic 1,1-addition of C–H bonds and aminating agents to terminal alkenes
α-Branched amines are present in hundreds of pharmaceutical agents and clinical candidates and are important targets for synthesis. Here we show the convergent synthesis of α-branched amines from three readily accessible starting materials: aromatic C–H bond substrates, terminal alkenes, and aminati...
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| Publicado no: | Nat Catal |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7462361/ https://ncbi.nlm.nih.gov/pubmed/32879907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41929-019-0330-7 |
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