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Information theoretic measures for quantifying sequence–ensemble relationships of intrinsically disordered proteins

Intrinsically disordered proteins (IDPs) contribute to a multitude of functions. De novo design of IDPs should open the door to modulating functions and phenotypes controlled by these systems. Recent design efforts have focused on compositional biases and specific sequence patterns as the design fea...

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Publicado en:Protein Eng Des Sel
Autores principales: Cohan, Megan C, Ruff, Kiersten M, Pappu, Rohit V
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462041/
https://ncbi.nlm.nih.gov/pubmed/31375817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzz014
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