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Information theoretic measures for quantifying sequence–ensemble relationships of intrinsically disordered proteins

Intrinsically disordered proteins (IDPs) contribute to a multitude of functions. De novo design of IDPs should open the door to modulating functions and phenotypes controlled by these systems. Recent design efforts have focused on compositional biases and specific sequence patterns as the design fea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Protein Eng Des Sel
Hauptverfasser: Cohan, Megan C, Ruff, Kiersten M, Pappu, Rohit V
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462041/
https://ncbi.nlm.nih.gov/pubmed/31375817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzz014
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