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Information theoretic measures for quantifying sequence–ensemble relationships of intrinsically disordered proteins

Intrinsically disordered proteins (IDPs) contribute to a multitude of functions. De novo design of IDPs should open the door to modulating functions and phenotypes controlled by these systems. Recent design efforts have focused on compositional biases and specific sequence patterns as the design fea...

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Dades bibliogràfiques
Publicat a:Protein Eng Des Sel
Autors principals: Cohan, Megan C, Ruff, Kiersten M, Pappu, Rohit V
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462041/
https://ncbi.nlm.nih.gov/pubmed/31375817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzz014
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