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Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity
Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of tissue-type (tPA) and urokinase-type (uPA) plasminogen activators (PAs). Apart from being critically involved in fibrinolysis and wound healing, emerging evidence indicates that PAI-1 plays an important role in many dis...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461574/ https://ncbi.nlm.nih.gov/pubmed/32824134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165859 |
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