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Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis

BACKGROUND: The mechanisms leading to extracellular matrix (ECM) replacement of areas of glomerular capillaries in histologic variants of FSGS are unknown. This study used proteomics to test the hypothesis that glomerular ECM composition in collapsing FSGS (cFSGS) differs from that of other variants...

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Опубликовано в: :J Am Soc Nephrol
Главные авторы: Merchant, Michael L., Barati, Michelle T., Caster, Dawn J., Hata, Jessica L., Hobeika, Liliane, Coventry, Susan, Brier, Michael E., Wilkey, Daniel W., Li, Ming, Rood, Ilse M., Deegens, Jeroen K., Wetzels, Jack F., Larsen, Christopher P., Troost, Jonathan P., Hodgin, Jeffrey B., Mariani, Laura H., Kretzler, Matthias, Klein, Jon B., McLeish, Kenneth R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460901/
https://ncbi.nlm.nih.gov/pubmed/32561683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019070696
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