Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis

BACKGROUND: The mechanisms leading to extracellular matrix (ECM) replacement of areas of glomerular capillaries in histologic variants of FSGS are unknown. This study used proteomics to test the hypothesis that glomerular ECM composition in collapsing FSGS (cFSGS) differs from that of other variants...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Merchant, Michael L., Barati, Michelle T., Caster, Dawn J., Hata, Jessica L., Hobeika, Liliane, Coventry, Susan, Brier, Michael E., Wilkey, Daniel W., Li, Ming, Rood, Ilse M., Deegens, Jeroen K., Wetzels, Jack F., Larsen, Christopher P., Troost, Jonathan P., Hodgin, Jeffrey B., Mariani, Laura H., Kretzler, Matthias, Klein, Jon B., McLeish, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460901/
https://ncbi.nlm.nih.gov/pubmed/32561683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019070696
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