IKKβ Kinase Promotes Stemness, Migration, and Invasion in KRAS-Driven Lung Adenocarcinoma Cells

KRAS oncogenic mutations are widespread in lung cancer and, because direct targeting of KRAS has proven to be challenging, KRAS-driven cancers lack effective therapies. One alternative strategy for developing KRAS targeted therapies is to identify downstream targets involved in promoting important m...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Rodrigues, Felipe Silva, Miranda, Vanessa Silva, Carneiro-Lobo, Tatiana Correa, Scalabrini, Luiza Coimbra, Kruspig, Björn, Levantini, Elena, Murphy, Daniel J., Bassères, Daniela Sanchez
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460870/
https://ncbi.nlm.nih.gov/pubmed/32823550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165806
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