Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway

BACKGROUND: Cisplatin (CDDP) is an effective anticancer drug for Gastric cancer (GC) that induces apoptosis by altering pro- (p53) and anti-apoptotic (Akt and NFkB) proteins; however, chemoresistance remains a big challenge. Additional compounds with promising anticancer effects such as AKBA (Acetyl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Pharmacol Toxicol
Main Authors: Al-Bahlani, Shadia, Burney, Ikram A., Al-Dhahli, Buthaina, Al-Kharusi, Safiya, Al-Kharousi, Fakhra, Al-Kalbani, Amani, Ahmed, Ikhlas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460741/
https://ncbi.nlm.nih.gov/pubmed/32867831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-00442-1
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