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Osteoclasts’ Ability to Generate Trenches Rather Than Pits Depends on High Levels of Active Cathepsin K and Efficient Clearance of Resorption Products

Until recently, it was well-accepted that osteoclasts resorb bone according to the resorption cycle model. This model is based on the assumption that osteoclasts are immobile during bone erosion, allowing the actin ring to be firmly attached and thereby provide an effective seal encircling the resor...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Borggaard, Xenia G., Pirapaharan, Dinisha C., Delaissé, Jean-Marie, Søe, Kent
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460581/
https://ncbi.nlm.nih.gov/pubmed/32824687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165924
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