Loading...

Inactivation of Genes by Frameshift Mutations Provides Rapid Adaptation of an Attenuated Vaccinia Virus

Unlike RNA viruses, most DNA viruses replicate their genomes with high-fidelity polymerases that rarely make base substitution errors. Nevertheless, experimental evolution studies have revealed rapid acquisition of adaptive mutations during serial passage of attenuated vaccinia virus (VACV). One way...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Senkevich, Tatiana G., Zhivkoplias, Erik K., Weisberg, Andrea S., Moss, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459559/
https://ncbi.nlm.nih.gov/pubmed/32669330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01053-20
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!