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Intestinal epithelial plasticity and regeneration via cell dedifferentiation

The intestinal epithelium possesses a great capacity of self-renewal under normal homeostatic conditions and of regeneration upon damages. The renewal and regenerative processes are driven by intestinal stem cells (ISCs), which reside at the base of crypts and are marked by Lgr5. As Lgr5(+) ISCs und...

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Bibliografiske detaljer
Udgivet i:Cell Regen
Main Authors: Liu, Yuan, Chen, Ye-Guang
Format: Artigo
Sprog:Inglês
Udgivet: Springer Singapore 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459029/
https://ncbi.nlm.nih.gov/pubmed/32869114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13619-020-00053-5
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