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Intestinal epithelial plasticity and regeneration via cell dedifferentiation

The intestinal epithelium possesses a great capacity of self-renewal under normal homeostatic conditions and of regeneration upon damages. The renewal and regenerative processes are driven by intestinal stem cells (ISCs), which reside at the base of crypts and are marked by Lgr5. As Lgr5(+) ISCs und...

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Detalhes bibliográficos
Publicado no:Cell Regen
Main Authors: Liu, Yuan, Chen, Ye-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459029/
https://ncbi.nlm.nih.gov/pubmed/32869114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13619-020-00053-5
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