Abundance and nuclear antigen reactivity of intestinal and fecal Immunoglobulin A in lupus-prone mice at younger ages correlate with the onset of eventual systemic autoimmunity

Our recent studies, using (SWRxNZB)F1 (SNF1) mice, showed a potential contribution of the gut microbiota and pro-inflammatory immune responses of the gut mucosa to systemic autoimmunity in lupus. Here, using this mouse model, we determined the abundance and the nAg reactivity of IgA antibody produce...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Sun, Wei, Gudi, Radhika R., Johnson, Benjamin M., Vasu, Chenthamarakshan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458927/
https://ncbi.nlm.nih.gov/pubmed/32868790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71272-8
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