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Gut microbiota differently contributes to intestinal immune phenotype and systemic autoimmune progression in female and male lupus-prone mice

The risk of developing systemic lupus erythematosus (SLE) is about 9 times higher in women as compared to men. Our recent report, which used (SWRxNZB) F1 (SNF1) mouse model of spontaneous lupus, showed a potential link between immune response initiated in the gut mucosa at juvenile age (sex hormone...

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Dettagli Bibliografici
Pubblicato in:J Autoimmun
Autori principali: Johnson, Benjamin M., Gaudreau, Marie-Claude, Gudi, Radhika, Brown, Robert, Gilkeson, Gary, Vasu, Chenthamarakshan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204266/
https://ncbi.nlm.nih.gov/pubmed/32019684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2020.102420
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