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PD-1(hi) CD8(+) resident memory T cells balance immunity and fibrotic sequelae

CD8(+) tissue-resident memory T (T(RM)) cells provide frontline immunity in mucosal tissues. The mechanisms regulating CD8(+) T(RM) maintenance, heterogeneity, and protective and pathological functions are largely elusive. Here, we identify a population of CD8(+) T(RM) cells that is maintained by ma...

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Dettagli Bibliografici
Pubblicato in:Sci Immunol
Autori principali: Wang, Zheng, Wang, Shaohua, Goplen, Nick P., Li, Chaofan, Cheon, In Su, Dai, Qigang, Huang, Su, Shan, Jinjun, Ma, Chaoyu, Ye, Zhenqing, Xiang, Min, Limper, Andrew H., Porquera, Eva-Carmona, Kohlmeier, Jacob E., Kaplan, Mark H., Zhang, Nu, Johnson, Aaron J., Vassallo, Robert, Sun, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458867/
https://ncbi.nlm.nih.gov/pubmed/31201259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaw1217
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