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Negatively charged amino acids in the stalk region of membrane proteins reduce ectodomain shedding
Ectodomain shedding is a post-translational modification mechanism by which the entire extracellular domain of membrane proteins is liberated through juxtamembrane processing. Because shedding rapidly and irreversibly alters the characteristics of cells, this process is properly regulated. However,...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7458810/ https://ncbi.nlm.nih.gov/pubmed/32580944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013758 |
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