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The role of circulating monocytes and JAK inhibition in the infectious-driven inflammatory response of myelofibrosis
Myelofibrosis (MF) is characterized by chronic inflammation and hyper-activation of the JAK-STAT pathway. Infections are one of the main causes of morbidity/mortality. Therapy with Ruxolitinib (RUX), a JAK1/2 inhibitor, may further increase the infectious risk. Monocytes are critical players in infl...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7458658/ https://ncbi.nlm.nih.gov/pubmed/32923146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1782575 |
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