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The role of circulating monocytes and JAK inhibition in the infectious-driven inflammatory response of myelofibrosis

Myelofibrosis (MF) is characterized by chronic inflammation and hyper-activation of the JAK-STAT pathway. Infections are one of the main causes of morbidity/mortality. Therapy with Ruxolitinib (RUX), a JAK1/2 inhibitor, may further increase the infectious risk. Monocytes are critical players in infl...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Barone, Martina, Catani, Lucia, Ricci, Francesca, Romano, Marco, Forte, Dorian, Auteri, Giuseppe, Bartoletti, Daniela, Ottaviani, Emanuela, Tazzari, Pier Luigi, Vianelli, Nicola, Cavo, Michele, Palandri, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458658/
https://ncbi.nlm.nih.gov/pubmed/32923146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1782575
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