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Attempt to Predict A/T/N-Based Alzheimer’s Disease Cerebrospinal Fluid Biomarkers Using a Peripheral Blood DNA Methylation Clock

BACKGROUND: Although aging is the strongest risk factor for the development of Alzheimer’s disease (AD), it remains uncertain if the blood DNA methylation clock, which reflects the effect of biological aging on DNA methylation (DNAme) status of blood cells, may be used as a surrogate biomarker for A...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis Rep
Main Authors: Sato, Kenichiro, Mano, Tatsuo, Suzuki, Kazushi, Toda, Tatsushi, Iwatsubo, Takeshi, Iwata, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458568/
https://ncbi.nlm.nih.gov/pubmed/32904719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-200205
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