Emergence of SARS-CoV-2 through recombination and strong purifying selection

COVID-19 has become a global pandemic caused by the novel coronavirus SARS-CoV-2. Understanding the origins of SARS-CoV-2 is critical for deterring future zoonosis, discovering new drugs, and developing a vaccine. We show evidence of strong purifying selection around the receptor binding motif (RBM)...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Li, Xiaojun, Giorgi, Elena E., Marichannegowda, Manukumar Honnayakanahalli, Foley, Brian, Xiao, Chuan, Kong, Xiang-Peng, Chen, Yue, Gnanakaran, S., Korber, Bette, Gao, Feng
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458444/
https://ncbi.nlm.nih.gov/pubmed/32937441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb9153
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