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Class IA PI3K regulatory subunits: p110-independent roles and structures

The phosphatidylinositol 3-kinase (PI3K) pathway is a critical regulator of many cellular processes including cell survival, growth, proliferation and motility. Not surprisingly therefore, the PI3K pathway is one of the most frequently mutated pathways in human cancers. In addition to their canonica...

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Библиографические подробности
Опубликовано в: :Biochem Soc Trans
Главные авторы: Fox, Millie, Mott, Helen R., Owen, Darerca
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458397/
https://ncbi.nlm.nih.gov/pubmed/32677674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190845
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