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Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation

Engineered nanoparticles could trigger inflammatory responses and potentiate a desired innate immune response for efficient immunotherapy. Here we report size-dependent activation of innate immune signaling pathways by gold (Au) nanoparticles. The ultrasmall-size (<10 nm) Au nanoparticles prefere...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Zhu, Motao, Du, Libo, Zhao, Ruifang, Wang, Helen Y., Zhao, Yuliang, Nie, Guangjun, Wang, Rong-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457719/
https://ncbi.nlm.nih.gov/pubmed/32057231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c00962
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