MCC950, a selective NLPR3 inflammasome inhibitor, improves neurologic function and survival after cardiac arrest and resuscitation

BACKGROUND: Cardiac arrest (CA) is associated with high morbidity and mortality, even after spontaneous circulation is re-established. This dire situation is partly due to post-CA syndrome for which no specific and effective intervention is available. One key component of post-CA syndrome is sterile...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Jiang, Maorong, Li, Ran, Lyu, Jingjun, Li, Xuan, Wang, Wei, Wang, Zhuoran, Sheng, Huaxin, Zhang, Weiguo, Karhausen, Jörn, Yang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457538/
https://ncbi.nlm.nih.gov/pubmed/32867797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01933-y
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