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AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations

BACKGROUND: Venous malformations (VMs), most of which associated with activating mutations in the endothelial cells (ECs) tyrosine kinase receptor TIE2, are characterized by dilated and immature veins with scarce smooth muscle cells (SMCs) coverage. However, the underlying mechanism of interaction b...

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Bibliografski detalji
Izdano u:Cell Commun Signal
Glavni autori: Si, Yameng, Huang, Jiadong, Li, Xiang, Fu, Yu, Xu, Rongyao, Du, Yifei, Cheng, Jie, Jiang, Hongbing
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457504/
https://ncbi.nlm.nih.gov/pubmed/32867785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00606-w
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