AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations

BACKGROUND: Venous malformations (VMs), most of which associated with activating mutations in the endothelial cells (ECs) tyrosine kinase receptor TIE2, are characterized by dilated and immature veins with scarce smooth muscle cells (SMCs) coverage. However, the underlying mechanism of interaction b...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Si, Yameng, Huang, Jiadong, Li, Xiang, Fu, Yu, Xu, Rongyao, Du, Yifei, Cheng, Jie, Jiang, Hongbing
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457504/
https://ncbi.nlm.nih.gov/pubmed/32867785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00606-w
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