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High Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States

Soluble methane monooxygenase (sMMO) is a multicomponent metalloenzyme that catalyzes the conversion of methane to methanol at ambient temperature using a nonheme, oxygen-bridged dinuclear iron cluster in the active site. Structural changes in the hydroxylase component (sMMOH) containing the diiron...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Srinivas, Vivek, Banerjee, Rahul, Lebrette, Hugo, Jones, Jason C., Aurelius, Oskar, Kim, In-Sik, Pham, Cindy C., Gul, Sheraz, Sutherlin, Kyle D., Bhowmick, Asmit, John, Juliane, Bozkurt, Esra, Fransson, Thomas, Aller, Pierre, Butryn, Agata, Bogacz, Isabel, Simon, Philipp, Keable, Stephen, Britz, Alexander, Tono, Kensuke, Kim, Kyung Sook, Park, Sang-Youn, Lee, Sang Jae, Park, Jaehyun, Alonso-Mori, Roberto, Fuller, Franklin D., Batyuk, Alexander, Brewster, Aaron S., Bergmann, Uwe, Sauter, Nicholas K., Orville, Allen M., Yachandra, Vittal K., Yano, Junko, Lipscomb, John D., Kern, Jan, Högbom, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457426/
https://ncbi.nlm.nih.gov/pubmed/32683863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05613
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