Novel design of (PEG-ylated)PAMAM-based nanoparticles for sustained delivery of BDNF to neurotoxin-injured differentiated neuroblastoma cells

Brain-derived neurotrophic factor (BDNF) is essential for the development and function of human neurons, therefore it is a promising target for neurodegenerative disorders treatment. Here, we studied BDNF-based electrostatic complex with dendrimer nanoparticles encapsulated in polyethylene glycol (P...

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Veröffentlicht in:J Nanobiotechnology
Hauptverfasser: Dąbkowska, Maria, Łuczkowska, Karolina, Rogińska, Dorota, Sobuś, Anna, Wasilewska, Monika, Ulańczyk, Zofia, Machaliński, Bogusław
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457365/
https://ncbi.nlm.nih.gov/pubmed/32867843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00673-8
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