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Preclinical Evaluation of Long-Term Neuroprotective Effects of BDNF-Engineered Mesenchymal Stromal Cells as Intravitreal Therapy for Chronic Retinal Degeneration in Rd6 Mutant Mice

This study aimed to investigate whether the transplantation of genetically engineered bone marrow-derived mesenchymal stromal cells (MSCs) to overexpress brain-derived neurotrophic factor (BDNF) could rescue the chronic degenerative process of slow retinal degeneration in the rd6 (retinal degenerati...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lejkowska, Renata, Kawa, Miłosz Piotr, Pius-Sadowska, Ewa, Rogińska, Dorota, Łuczkowska, Karolina, Machaliński, Bogusław, Machalińska, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387230/
https://ncbi.nlm.nih.gov/pubmed/30759764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030777
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