Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

The aim of the study was to investigate the influence of complement component C3 global depletion on the biological structure and function of the aged retina. In vivo morphology (OCT), electrophysiological function (ERG), and the expression of selected oxidative stress-, apoptosis-, and autophagy-re...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Rogińska, Dorota, Kawa, Miłosz P., Pius-Sadowska, Ewa, Lejkowska, Renata, Łuczkowska, Karolina, Wiszniewska, Barbara, Kaarniranta, Kai, Paterno, Jussi J., Schmidt, Christian A., Machaliński, Bogusław, Machalińska, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591916/
https://ncbi.nlm.nih.gov/pubmed/28928904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5306790
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