Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome

Activation of the NLRP3 inflammasome is critical for host defense as well as the progression of inflammatory diseases through the production of the proinflammatory cytokine IL-1β, which is cleaved by active caspase-1. It has been reported that overactivation of the NLRP3 inflammasome contributes to...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Yang, Gabsik, Lee, Seon Joo, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Zouboulis, Christos C., Han, Sin-Hee, Ma, Kyung-Ho, Jang, Jae-Ki, Lee, Joo Young
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457177/
https://ncbi.nlm.nih.gov/pubmed/32319265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.004
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