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Auranofin, as an anti-rheumatic gold compound suppresses LPS-induced homodimerization of TLR4

Toll-like receptors (TLRs), which are activated by invading microorganisms or endogenous molecules, evoke immune and inflammatory responses. TLR activation is closely linked to the development of many chronic inflammatory diseases including rheumatoid arthritis. Auranofin, an Au(I) compound, is a we...

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Detalhes bibliográficos
Main Authors: Youn, Hyung S., Lee, Joo Y., Saitoh, Shin I., Miyake, Kensuke, Hwang, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668920/
https://ncbi.nlm.nih.gov/pubmed/17034761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.097
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