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Auranofin, as an anti-rheumatic gold compound suppresses LPS-induced homodimerization of TLR4
Toll-like receptors (TLRs), which are activated by invading microorganisms or endogenous molecules, evoke immune and inflammatory responses. TLR activation is closely linked to the development of many chronic inflammatory diseases including rheumatoid arthritis. Auranofin, an Au(I) compound, is a we...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668920/ https://ncbi.nlm.nih.gov/pubmed/17034761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.097 |
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