Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway

The thioredoxin (Trx) system plays critical roles in regulating intracellular redox levels and defending organisms against oxidative stress. Recent studies indicated that Trx reductase (TrxR) was overexpressed in various types of human cancer cells indicating that the Trx-TrxR system may be a potent...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Hwangbo, Hyun, Kim, So Young, Lee, Hyesook, Park, Shin-Hyung, Hong, Su Hyun, Park, Cheol, Kim, Gi-Young, Leem, Sun-Hee, Hyun, Jin Won, Cheong, Jaehun, Choi, Yung Hyun
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457169/
https://ncbi.nlm.nih.gov/pubmed/32856616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.122
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