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Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway

The thioredoxin (Trx) system plays critical roles in regulating intracellular redox levels and defending organisms against oxidative stress. Recent studies indicated that Trx reductase (TrxR) was overexpressed in various types of human cancer cells indicating that the Trx-TrxR system may be a potent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomol Ther (Seoul)
Hauptverfasser: Hwangbo, Hyun, Kim, So Young, Lee, Hyesook, Park, Shin-Hyung, Hong, Su Hyun, Park, Cheol, Kim, Gi-Young, Leem, Sun-Hee, Hyun, Jin Won, Cheong, Jaehun, Choi, Yung Hyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Applied Pharmacology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457169/
https://ncbi.nlm.nih.gov/pubmed/32856616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.122
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