Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway

Hepatocellular carcinoma (HCC) has a high mortality rate worldwide, and treatment is very limited due to its high recurrence and low diagnosis rate, and therefore there is an increasing need to develop more effective drugs to treat HCC. Coptisine is one of the isoquinoline alkaloids, and it has vari...

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Publicado no:Int J Mol Sci
Main Authors: Kim, So Young, Hwangbo, Hyun, Lee, Hyesook, Park, Cheol, Kim, Gi-Young, Moon, Sung-Kwon, Yun, Seok Joong, Kim, Wun-Jae, Cheong, Jaehun, Choi, Yung Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432186/
https://ncbi.nlm.nih.gov/pubmed/32752099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21155502
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