Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway

Hepatocellular carcinoma (HCC) has a high mortality rate worldwide, and treatment is very limited due to its high recurrence and low diagnosis rate, and therefore there is an increasing need to develop more effective drugs to treat HCC. Coptisine is one of the isoquinoline alkaloids, and it has vari...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Kim, So Young, Hwangbo, Hyun, Lee, Hyesook, Park, Cheol, Kim, Gi-Young, Moon, Sung-Kwon, Yun, Seok Joong, Kim, Wun-Jae, Cheong, Jaehun, Choi, Yung Hyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432186/
https://ncbi.nlm.nih.gov/pubmed/32752099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21155502
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