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Diclofenac Inhibits Phorbol Ester-Induced Gene Expression and Production of MUC5AC Mucin via Affecting Degradation of IkBα and Translocation of NF-kB p65 in NCI-H292 Cells

In this study, diclofenac, a non-steroidal anti-inflammatory drug, was investigated for its potential effect on the gene expression and production of airway MUC5AC mucin. The human respiratory epithelial NCI-H292 cells were pretreated with diclofenac for 30 min and stimulated with phorbol 12-myrista...

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Dettagli Bibliografici
Pubblicato in:Biomol Ther (Seoul)
Autori principali: Jin, Fengri, Li, Xin, Lee, Hyun Jae, Lee, Choong Jae
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society of Applied Pharmacology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457166/
https://ncbi.nlm.nih.gov/pubmed/32753566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.090
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