Transforming Growth Factor β Inhibits MUC5AC Expression by Smad3/HDAC2 Complex Formation and NF-κB Deacetylation at K310 in NCI-H292 Cells

Airway mucus secretion is an essential innate immune response for host protection. However, overproduction and hypersecretion of mucus, mainly composed of the gel-forming MUC5AC protein, are significant risk factors for patients with asthma and chronic obstructive pulmonary disease (COPD). The trans...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Cells
Hauptverfasser: Lee, Su Ui, Kim, Mun-Ock, Kang, Myung-Ji, Oh, Eun Sol, Ro, Hyunju, Lee, Ro Woon, Song, Yu Na, Jung, Sunin, Lee, Jae-Won, Lee, Soo Yun, Bae, Taeyeol, Hong, Sung-Tae, Kim, Tae-Don
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Molecular and Cellular Biology 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854180/
https://ncbi.nlm.nih.gov/pubmed/33510050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2020.0188
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge