All-trans Retinoic Acid Counteracts Diarrhea and Inhibition of Downregulated in Adenoma Expression in Gut Inflammation

BACKGROUND: Intestinal epithelial apical membrane Cl(-)/HCO(3)(-) exchanger DRA (downregulated in adenoma, SLC26A3) has emerged as an important therapeutic target for diarrhea, emphasizing the potential therapeutic role of agents that upregulate DRA. All-trans retinoic acid (ATRA), a key vitamin A m...

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Bibliografiske detaljer
Udgivet i:Inflamm Bowel Dis
Main Authors: Priyamvada, Shubha, Anbazhagan, Arivarasu N, Kumar, Anoop, Chatterjee, Ishita, Borthakur, Alip, Saksena, Seema, Gill, Ravinder K, Alrefai, Waddah A, Dudeja, Pradeep K
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Basic Science Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456978/
https://ncbi.nlm.nih.gov/pubmed/31634391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izz249
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