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A Novel Serine Phosphorylation Site Detected in the N-Terminal Domain of Estrogen Receptor Isolated from Human Breast Cancer Cells

Activated estrogen receptor (ERα) plays a critical role in breast cancer development and is a major target for drug treatment. Serine phosphorylation within the N-terminal domain (NTD) contributes to ERα activation and may also cause drug resistance. Previous biochemical identification of phosphoryl...

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Библиографические подробности
Опубликовано в: :J Am Soc Mass Spectrom
Главные авторы: Britton, David J., Scott, Gary K., Schilling, Birgit, Atsriku, Christian, Held, Jason M., Gibson, Bradford W., Benz, Christopher C., Baldwin, Michael A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456516/
https://ncbi.nlm.nih.gov/pubmed/18367407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2008.02.008
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