Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease as well as Lou Gehrig's disease, is a progressive neurological disorder selectively affecting motor neurons with no currently known cure. Around 20% of the familial ALS cases arise from dominant mutations in the...

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Gepubliceerd in:EBioMedicine
Hoofdauteurs: Amporndanai, Kangsa, Rogers, Michael, Watanabe, Seiji, Yamanaka, Koji, O'Neill, Paul M., Hasnain, S. Samar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456458/
https://ncbi.nlm.nih.gov/pubmed/32862101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102980
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