Gut Resistome After Oral Antibiotics in Preschool Children in Burkina Faso: A Randomized, Controlled Trial

We evaluated the effect of systemic antibiotics (azithromycin, amoxicillin, cotrimoxazole, or placebo) on the gut resistome in children aged 6 to 59 months. Azithromycin and cotrimoxazole led to an increase in macrolide and sulfonamide resistance determinants. Resistome expansion can be induced with...

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Détails bibliographiques
Publié dans:Clin Infect Dis
Auteurs principaux: Oldenburg, Catherine E, Hinterwirth, Armin, Sié, Ali, Coulibaly, Boubacar, Ouermi, Lucienne, Dah, Clarisse, Tapsoba, Charlemagne, Cummings, Susie L, Zhong, Lina, Chen, Cindi, Sarkar, Samarpita, Bärnighausen, Till, Lietman, Thomas M, Keenan, Jeremy D, Doan, Thuy
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Brief Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456340/
https://ncbi.nlm.nih.gov/pubmed/31149703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz455
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