Gut Resistome After Oral Antibiotics in Preschool Children in Burkina Faso: A Randomized, Controlled Trial

We evaluated the effect of systemic antibiotics (azithromycin, amoxicillin, cotrimoxazole, or placebo) on the gut resistome in children aged 6 to 59 months. Azithromycin and cotrimoxazole led to an increase in macrolide and sulfonamide resistance determinants. Resistome expansion can be induced with...

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Dades bibliogràfiques
Publicat a:Clin Infect Dis
Autors principals: Oldenburg, Catherine E, Hinterwirth, Armin, Sié, Ali, Coulibaly, Boubacar, Ouermi, Lucienne, Dah, Clarisse, Tapsoba, Charlemagne, Cummings, Susie L, Zhong, Lina, Chen, Cindi, Sarkar, Samarpita, Bärnighausen, Till, Lietman, Thomas M, Keenan, Jeremy D, Doan, Thuy
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456340/
https://ncbi.nlm.nih.gov/pubmed/31149703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz455
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