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Melanocortin-4 receptor antagonist TCMCB07 ameliorates cancer- and chronic kidney disease–associated cachexia

Cachexia, a devastating wasting syndrome characterized by severe weight loss with specific losses of muscle and adipose tissue, is driven by reduced food intake, increased energy expenditure, excess catabolism, and inflammation. Cachexia is associated with poor prognosis and high mortality and frequ...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhu, Xinxia, Callahan, Michael F., Gruber, Kenneth A., Szumowski, Marek, Marks, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456235/
https://ncbi.nlm.nih.gov/pubmed/32544087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138392
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