Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300

Fibrotic diseases remain a major cause of morbidity and mortality, yet there are few effective therapies. The underlying pathology of all fibrotic conditions is the activity of myofibroblasts. Using cells from freshly excised disease tissue from patients with Dupuytren’s disease (DD), a localized fi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Williams, Lynn M., McCann, Fiona E., Cabrita, Marisa A., Layton, Thomas, Cribbs, Adam, Knezevic, Bogdan, Fang, Hai, Knight, Julian, Zhang, Mingjun, Fischer, Roman, Bonham, Sarah, Steenbeek, Leenart M., Yang, Nan, Sood, Manu, Bainbridge, Chris, Warwick, David, Harry, Lorraine, Davidson, Dominique, Xie, Weilin, Sundstrӧm, Michael, Feldmann, Marc, Nanchahal, Jagdeep
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456151/
https://ncbi.nlm.nih.gov/pubmed/32759223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004281117
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